Grape and Grain is a neighborhood wine bar and restaurant specializing in small plates and a constantly rotating list of eclectic wines. We serve dinner seven nights a week and are open for brunch on weekends. Grape and Grain is located at 620 East 6th St. between Ave B. and Ave C.

We accept reservations, which can be made by leaving a message at 212-420-0002. Reservations are also available for our adjacent craft beer bar, Against the Grain, which is ideal for groups of 12-30 people.

Our weekly hours are as follows:
Monday - Tuesday 5:00 pm - 1:00 am
Wednesday - Friday 5:00 pm - 2:00 am
Saturday 10:30 am - 2:00 am
Sunday 10:30 am - 1:00 am